Fos-like immunoreactivity in the periaqueductal gray of rats exposed to a natural predator
Fos-like immunoreactivity in the periaqueductal gray of rats exposed to a natural predator
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DOI：
10.1097/00001756-199902050-00037
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发表时间：
1999-02-05
期刊：
影响因子：
1.7
通讯作者：
Goto, M
中科院分区：
文献类型：
--
作者：
Canteras, NS;Goto, M
在本研究中，我们研究了，在大鼠暴露于捕食者（猫），表达Fos的神经元分布沿着由中央灰质周围的尾极的第三脑室和周围的导水管灰质（PAG）形成的连续体。捕食遭遇后，Fos免疫反应阳性细胞的一个明显的集群观察到前连合核。在FAG的吻侧2/3区域，Fos表达主要见于背内侧和背外侧区域。相反，在尾侧水平的FAG，大部分的Fos标记神经元分布在外侧和腹外侧的FAG。这些结果进行了讨论，并与模式的FAG激活后的恐惧条件的上下文或引起的厌恶性足电击。(C)1999年利平科特威廉姆斯&威尔金斯。
IN the present study we examined, in rats exposed to a predator (cat), the distribution of neurons expressing Fos along the continuum formed by the central gray surrounding the caudal pole of the third ventricle and the periaqueductal gray (PAG). After the predatory encounter, a distinct cluster of Fos-immunoreactive cells was observed in the precommissural nucleus. In the rostral two-thirds of the FAG, Fos expression was mostly seen in the dorsomedial and dorsolateral regions. In contrast, at caudal levels of the FAG, most of the Fos-labelled neurons were distributed in the lateral and ventrolateral FAG. These results are discussed and compared with the pattern of the FAG activation after fear conditioned to a context or elicited by aversive foot shock. (C) 1999 Lippincott Williams & Wilkins.