Gender differences in the association between childhood abuse and psychosis

Gender differences in the association between childhood abuse and psychosis
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DOI:
10.1192/bjp.bp.107.047985
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发表时间:
2009-04-01
影响因子:
10.5
通讯作者:
Fearon, Paul
Fearon, Paul
中科院分区:
医学1区
文献类型:
--
作者:
Fisher, Helen;Morgan, Craig;Fearon, Paul

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研究背景儿童期创伤与成年期精神病之间的相关性研究尚未系统地探讨性别差异。目的探讨精神病患者与健康对照组儿童期性虐待和身体虐待患病率的性别差异。方法完成儿童期护理和虐待问卷调查,以了解儿童期性虐待和身体虐待的经历。发作精神病病例和人口为基础的controls.ResultsAmong妇女,那些在案件组的两倍可能报告身体或性虐待与对照组相比,调整后的所有混杂因素。特别是,身体虐待对妇女的影响比性虐待的影响更大。在女性对照组中发现类似精神病的经历也有类似的趋势。没有协会被发现在manifest.ConclusionsReports严重的儿童身体或性虐待与精神病的妇女,但不是在男性。
BackgroundStudies demonstrating an association between childhood trauma and psychosis in adulthood have not systematically explored gender differences.AimsTo investigate gender differences in the prevalence of childhood sexual and physical abuse among people with psychosis in comparison with healthy controls.MethodThe Childhood Experiences of Care and Abuse Questionnaire was completed to elicit experiences of sexual and physical abuse during childhood in first-episode psychosis cases and population-based controls.ResultsAmong women, those in the cases group were twice as likely to report either physical or sexual abuse compared with controls following adjustment for all confounders. In particular, the effect of physical abuse in women was stronger and more robust than that for sexual abuse. A similar trend was found for psychotic-like experiences in the female control group. No association was found in men.ConclusionsReports of severe childhood physical or sexual abuse were associated with psychosis in women but not in men.