Characterization of the coordination of agonist and antagonist muscles among stroke patients, healthy late middle-aged and young controls using a myoelectric-controlled interface
Characterization of the coordination of agonist and antagonist muscles among stroke patients, healthy late middle-aged and young controls using a myoelectric-controlled interface
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DOI：
10.1088/1741-2552/aad387
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发表时间：
2018-10-01
影响因子：
4
通讯作者：
Song, Rong
中科院分区：
文献类型：
--
作者：
Luo, Jie;Sun, Wenbo;Song, Rong
客观的。单个关节周围主动肌和拮抗肌的协调在日常活动中起着重要作用。本研究的目的是应用不同尺寸的肌电控制接口（MCI）来研究中风和衰老引起的主动肌和拮抗肌协调性恶化。方法。 8 名中风患者（受影响侧）、10 名健康中年晚期对照者和 18 名健康年轻对照者被招募，通过用 1D 或 2D MCI 调节他们的二头肌和三头肌活动，在自愿等距肘部屈曲和伸展期间执行跟踪任务。实际和目标激动剂激活之间的均方根误差（RMSE）、标准化激动剂和拮抗剂激活以及共同收缩指数（CI）和标准化肘部扭矩用于量化运动性能。主要结果。在肘部伸展期间，随着 MCI 维数的增加，中风患者的 RMSE 显着增加，而在所有三组中都观察到标准化激动剂和拮抗剂激活以及标准化肘部扭矩显着下降。此外，两个对照组的 CI 均显着下降（P < 0.05）。在肘关节屈曲和伸展过程中，RMSE 按以下顺序增加：年轻对照者 < 中年晚期对照者 < 中风患者。相比之下，中风患者和中年晚期对照组的 CI 明显高于年轻对照组，这可能是由于中风和衰老导致在满足不断变化的环境需求时调节主动肌和拮抗肌协调的技能丧失。意义。这项研究表明，2D MCI 可以作为一种康复工具来实现对异常肌肉协调的精细控制。
Objective. The coordination of agonist and antagonist muscles around a single joint plays an important role in daily activities. The aim of this study was to apply a myoelectric-controlled interface (MCI) with different dimensions to investigate stroke- and aging-induced deteriorations in the coordination of agonist and antagonist muscles. Approach. Eight stroke patients (affected sides), ten healthy late middle-aged controls and eighteen healthy young controls were enrolled to perform tracking tasks during voluntary isometric elbow flexion and extension by modulating their biceps and triceps activities with 1D or 2D MCI. The root mean square error (RMSE) between actual and target agonist activations, normalized agonist and antagonist activations, and co-contraction index (CI) and normalized elbow torque were used to quantify the movement performance. Main results. During elbow extension, significant increases in RMSE were identified in stroke patients with increasing MCI dimensionality, whereas significant decreases in normalized agonist and antagonist activations and normalized elbow torque were observed in all three groups. In addition, significant decreases in CI were observed in both control groups (P < 0.05). During elbow flexion and extension, RMSE increased in the following order: young controls < late middle-aged controls < stroke patients. By contrast, CI was significantly higher in stroke patients and late middle-aged controls than in young controls, possibly due to stroke-and aging-induced loss of skill in modulating the coordination of agonist and antagonist muscles when meeting the demands of a changing environment. Significance. This study suggests that 2D MCI might be applied as a rehabilitation tool to achieve fine control of abnormal muscle coordination.