Non-synaptic neuronal mechanisms of learning and memory in gastropod molluscs
Non-synaptic neuronal mechanisms of learning and memory in gastropod molluscs
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DOI：
10.2741/2993
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发表时间：
2008-05-01
期刊：
影响因子：
--
通讯作者：
Kemenes, Ildiko
中科院分区：
文献类型：
--
作者：
Benjamin, Paul R.;Kemenes, Gyoergy;Kemenes, Ildiko
腹足类软体动物为研究联想和非联想学习的行为和神经基础提供了重要的模型系统。在运动反射和中枢模式发生器回路中研究习惯化、敏化、经典和操作性条件反射。虽然突触可塑性一直被认为在软体动物的学习回路中起着关键作用，但非突触变化导致神经元兴奋性的改变越来越被认为是记忆痕迹的重要组成部分。
Gastropod molluscs provide important model systems for investigating the behavioral and neural basis of associative and non-associative learning. Habituation, sensitization, classical and operant conditioning are studied in motor reflex and central pattern generator circuits. Although synaptic plasticity has long been recognized as playing a key role in molluscan learning circuits, non-synaptic changes resulting in alterations in the excitability of neurons are increasingly recognized as an essential component of the memory trace.