Personal sensors for the diagnosis and management of metabolic disorders.

Personal sensors for the diagnosis and management of metabolic disorders.
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用于诊断和管理代谢紊乱的个人传感器。

DOI:
10.1109/memb.2003.1191447
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发表时间:
2003
期刊:
IEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society
影响因子:
--
通讯作者:
Andrade,Joseph
Andrade,Joseph
中科院分区:
--
文献类型:
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作者:
Davies,Rupert;Bartholomeusz,DanielA;Andrade,Joseph

文献摘要

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基于发光的分析,便于在床旁或家庭环境中使用的小样本量中测量多种代谢物。我们对这个项目的部分兴趣在于患者赋权-让患者承担责任并控制自己的疾病。我们的目标是一个化学芯片系统,类似于目前一代的葡萄糖试纸和血糖仪在易用性,数据质量和低成本方面。如果化学芯片的潜力得以实现,几乎所有相关的疾病标志物在广泛的分子量和浓度范围内都可以定量和特异性地测量,用于疾病诊断和管理。
Luminescence-based analysis that facilitates the measurement of multiple metabolites from small sample volumes for use in point-of-care or in-home environments. Part of our interest in this project is in patient empowerment-getting patients to assume responsibility and control of their own diseases. Our goal is a Chem-Chip system that is analogous to the present generation of glucose dipsticks and glucometers in terms of ease of use, quality of data, and low cost. If the potential of the Chem-Chip is realized, practically all relevant disease markers over a wide range of molecular weights and concentrations could be quantitatively and specifically measured for disease diagnosis and management.