Raman fingerprints of amyloid structures

Raman fingerprints of amyloid structures
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DOI:
10.1039/c8cc03217c
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发表时间:
2018-06-28
影响因子:
4.9
通讯作者:
Lee, Jennifer C.
Lee, Jennifer C.
中科院分区:
化学2区
文献类型:
--
作者:
Flynn, Jessica D.;Lee, Jennifer C.

文献摘要

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Structural differences in pathological and functional amyloid fibrils have been investigated by Raman microspectroscopy. Second-derivative analyses of amide-I and amide-III bands distinguish parallel in-register beta-sheets from a beta-solenoid. Further, spatially resolved Raman spectra reveal molecular heterogeneity in amyloid structures.