The accuracy of date of death recording in the Clinical Practice Research Datalink GOLD database in England compared with the Office for National Statistics death registrations
The accuracy of date of death recording in the Clinical Practice Research Datalink GOLD database in England compared with the Office for National Statistics death registrations
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DOI：
10.1002/pds.4747
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发表时间：
2019-05-01
影响因子：
2.6
通讯作者：
de Vries, Frank
中科院分区：
文献类型：
--
作者：
Gallagher, Arlene M.;Dedman, Daniel;de Vries, Frank
目的：目前尚不清楚是否所有死亡都记录在临床实践研究数据链（CPRD）中，也不清楚记录的死亡日期有多准确。与英国国家统计局（ONS）和医院事件统计局（HES）的国家数据的个人层面联系提供了比较不同数据来源的死亡信息的机会。将2013年欧洲标准人口（ESP）标准化的CPRD标准化死亡率（ASMR）与ONS公布的数字进行比较，计算样本人群的粗死亡率，CPRD、ONS和HES数据之间存在个体关联。结果：ONS数据中有33997例患者有死亡记录，其中33389例（98.2%）也在CPRD中被识别。在整个研究期间，CPRD和ONS之间死亡日期的准确一致率为69.7%，从1998年的53.4%增加到2013年的78.0%。到2013年，98.8%的死亡在+/- 30 days.Conclusions内达成一致：对于删失随访和计算死亡率，CPRD数据可能足够，因为死亡记录延迟长达1个月不太可能显著影响结果。如果死亡的确切日期或原因很重要，则建议纳入ONS的个体关联死亡登记数据。
Purpose: It is not clear whether all deaths are recorded in the Clinical Practice Research Datalink (CPRD) or how accurate a recorded date of death is. Individual-level linkage with national data from the Office for National Statistics (ONS) and Hospital Episode Statistics (HES) in England offers the opportunity to compare death information across different data sources.Methods: Age-standardised mortality rates (ASMRs) standardised to the European Standard Population (ESP) 2013 for CPRD were compared with figures published by the ONS, and crude mortality rates were calculated for a sample population with individual linkage between CPRD, ONS, and HES data. Agreement on the fact of death between CPRD and ONS was assessed and presented over time from 1998 to 2013.Results: There were 33 997 patients with a record of death in the ONS data; 33 389 (98.2%) of these were also identified in CPRD. Exact agreement on the death date between CPRD and the ONS was 69.7% across the whole study period, increasing from 53.4% in 1998 to 78.0% in 2013. By 2013, 98.8% of deaths were in agreement within +/- 30 days.Conclusions: For censoring follow-up and calculating mortality rates, CPRD data are likely to be sufficient, as a delay in death recording of up to 1 month is unlikely to impact results significantly. Where the exact date of death or the cause is important, it may be advisable to include the individually linked death registration data from the ONS.