Carbon nanotubes in electrochemical, colorimetric, and fluorimetric immunosensors and immunoassays: a review
Carbon nanotubes in electrochemical, colorimetric, and fluorimetric immunosensors and immunoassays: a review
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碳纳米管在电化学、比色和荧光免疫传感器和免疫测定中的应用：综述
DOI：
10.1007/s00604-020-4172-4
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发表时间：
2020
影响因子：
5.7
通讯作者：
Yu Zhou
中科院分区：
文献类型：
--
作者：
Hualin Yang;Wentao Xu;Xiongyan Liang;Yuying Yang;Yu Zhou
本文综述了碳纳米管在免疫分析和免疫传感器中的应用进展。在对该领域的介绍之后，第一个大部分涵盖了作为抗体载体的官能团修饰的CNT（用氨基、羧基和各种其他材料修饰的CNT的子部分）。下一节将碳纳米管与无机或有机材料耦合作为活性组分（使用纳米粒子，如Fe 3 O 4，ZnO，金）或与氧化铟锡（ITO），NiCoBP，离子液体，TiO 2纳米片，金属簇;壳聚糖，聚苯乙烯，聚多巴胺，石墨烯或酶。另一部分讨论了CNT与金属、金属离子和有机/无机材料的协同效应。几个表格给出了方法和材料的财富的概述。最后一节总结了目前的状态，解决当前的挑战，并给出了未来的潜在trends.Graphical abstraction的碳纳米管（CNT）在免疫传感器和免疫测定的作用的前景。(I)功能基团修饰的碳纳米管作为抗体的载体;（II）碳纳米管与金属或有机材料偶联作为活性组分;和（III）碳纳米管与其他材料的协同效应，以改善免疫传感器的参数。
This review (with 126 references) summarizes the progress that has been made in the use of carbon nanotubes (CNTs) in immunoassays and immunosensors. Following an introduction into the field, a first large section covers functional group-modified CNTs as carriers for antibodies (with subsections on CNTs modified with amino, carboxy and by various other materials). The next section treats CNTs coupled with inorganic or organic materials as active components (with the use of nanoparticles such as Fe3O4, ZnO, gold) or with indium tin oxide (ITO), NiCoBP, ionic liquids, TiO2nanosheets, metal clusters; chitosan, polystyrene, polydopamine, graphene, or enzymes. Another section discusses the synergistic effects of CNTs with metals, metal ions, and organic/inorganic materials. Several Tables are presented that give an overview on the wealth of methods and materials. A concluding section summarizes the current status, addresses current challenges, and gives an outlook on potential future trends.Graphical abstractSchematic presentation of the roles of carbon nanotubes (CNTs) in immunosensors and immunoassays. (I) Functional group-modified CNTs as carriers for antibody; (II) CNTs coupled with metal or organic materials as active component; and (III) Synergistic effects of CNTs with other materials to improve the parameters of immunosensors.