TERNARY-SYSTEMS WITH 1,2-PROPANEDIOL - A NEW GAIN IN THE STABILITY OF THE AMORPHOUS STATE IN THE SYSTEM WATER-1,2-PROPANEDIOL-1-PROPANOL
TERNARY-SYSTEMS WITH 1,2-PROPANEDIOL - A NEW GAIN IN THE STABILITY OF THE AMORPHOUS STATE IN THE SYSTEM WATER-1,2-PROPANEDIOL-1-PROPANOL
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DOI：
10.1016/0011-2240(82)90184-5
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发表时间：
1982-01-01
期刊：
影响因子：
2.7
通讯作者：
KORBER, C
中科院分区：
文献类型：
--
作者：
BOUTRON, P;DELAGE, D;KORBER, C
研究了水和1，2-丙二醇三元体系，第三组分为1-丙醇、乙醇或甘油。丙醇和乙醇在其水溶液和这些三元体系中生成水合物，而甘油则不生成水合物。乙醇部分取代1，2-丙二醇时，在相同水分含量下，无定形状态的稳定性和玻璃的形成倾向没有增加。当它被甘油部分取代时，增益可以忽略不计。相反，当水含量为65%(wt/wt)时，正丙醇取代15%(wt/wt)的1，2-丙二醇时，体系的非晶态稳定性达到极大值，临界升温速率从108℃/min降至1040℃/min。与少量水合物晶化相对应，这种置换对玻璃形成倾向的影响很小。不仅非晶态的稳定性较高，而且在某些情况下，在较低温度下用笼状结晶取代冰结晶可能有助于在一定的降温和升温速率下对细胞进行更好的冷冻保护。所研究的三元体系之间的相似之处使我们对这些体系的一般行为有了一个了解。
Three ternary systems with water and 1,2-propanediol were investigated, where the 3rd component is 1-propranol, ethanol or glycerol. 1-Propanol and ethanol give hydrates in their aqueous solutions as well as in these ternary systems, while glycerol gives none. No gain in the stability of the amorphous state and glass-formation tendency is obtained for the same water contents when 1,2-propanediol is partially replaced by ethanol. The gain is negligible when it is partially replaced by glycerol. On the contrary, a large maximum in the stability of the amorphous state is obtained, with a critical warming rate dropping from 108 to 1040C/min in the presence of 65% (wt/wt) water when 15% (wt/wt) of the 1,2-propanediol is replaced by 1-propanol. The decrease in the glass formation tendency due to this replacement and corresponding to a few hydrate crystallization is small. Not only the higher stability of the amorphous state, but also in some cases the replacement of ice crystallization by clathrate crystallinization at lower temperatures could perhaps contribute to a better cryoprotection of cells for some cooling and warming rates. The similarities observed between the ternary systems investigated gives an idea of the general behavior of these systems.