PARTURITION - ITS ROLE IN LONG-TERM RETENTION OF MATERNAL-BEHAVIOR IN RAT
PARTURITION - ITS ROLE IN LONG-TERM RETENTION OF MATERNAL-BEHAVIOR IN RAT
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DOI：
10.1016/0031-9384(77)90263-3
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发表时间：
1977-01-01
影响因子：
2.9
通讯作者：
BRIDGES, RS
中科院分区：
文献类型：
--
作者：
BRIDGES, RS
研究了分娩在建立大鼠母性行为长期保留中的作用。妊娠第 22 天剖腹产且手术后立即（< 22 小时）有母体反应的初孕大鼠被允许对测试幼崽进行母体喂养 48-70 小时，此时将测试幼崽与实验动物分开。大约 25 天后，当再次暴露于幼鼠时，50% 的剖腹产动物在 1 小时内做出母性反应，而其余 50% 在 5 个测试天内做出母性反应。剖腹产动物的母体反应水平与产后仅接受 2 天的幼仔暴露，然后在 25 天后测试母体行为的保留的初产动物没有差异。在清除仔猪后 25 天的第一个测试期间，42% 的初产动物做出了母性反应。尽管在初次致敏期后 25 天再次暴露于幼鼠后，未产过的动物的母性反应潜伏期明显缩短，但剖腹产动物和初产动物的母性反应明显快于先前致敏的未产过的雌性。分娩行为对于大鼠母性行为的长期保留并不是必需的。终止妊娠后与幼崽接触可能有助于强化母性行为保留的过程。
The role of parturition in the establishment of the long-term retention of maternal behavior in the rat was investigated. Primigravid rats cesarean sectioned on day 22 of gestation that responded maternally immediately (< 22 h) following surgery were permitted to be maternal towards test pups for 48-70 h at which time test pups were separated from the experimental animals. When reexposed to rat pups some 25 days later 50% of the cesarean sectioned animals responded maternally within 1 h while the remaining 50% responded maternally within 5 test days. The level of maternal responsiveness of cesarean sectioned animals did not differ from that of primiparous animals given only 2 days of pup exposure postpartum and then tested for the retention of maternal behavior 25 days later. Forty-two percent of the primiparous animals responded maternally during the 1st test period 25 days following litter removal. Although a slight reduction in latency to respond maternally was evident in nulliparous animals upon reexposure to rat pups 25 days after an initial sensitization period, both cesarean sectioned and primiparous animals responded maternally significantly faster than did previously sensitized nulliparous females. The act of parturition is not essential for the establishment of the long-term retention of maternal behavior in the rat. Exposure to pups following termination of pregnancy may serve to intensify the process whereby the retention of maternal behavior is established.