The role of galectin‐3 in heart failure and cardiovascular disease
The role of galectin‐3 in heart failure and cardiovascular disease
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DOI：
10.1111/1440-1681.13048
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发表时间：
2019
期刊：
影响因子：
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通讯作者：
Xiang Song
中科院分区：
文献类型：
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作者：
Xiao Zhong;Xiaoqian Qian;Guangping Chen;Xiang Song
Galectin‐3, a β‐galactoside‐binding lectin, is a new important player in the progression of heart failure (HF) and is also linked to poor outcome in patients with cardiovascular disease. Genetic or pharmacological inhibition of galectin‐3 slows down the progression of myocardial inflammation, reduces collagen production, attenuates cardiac remodelling, and ameliorates cardiac function. In this review, we summarize recent progress in research on galectin‐3 as a regulatory molecule involved in cardiovascular fibrosis in HF and its potential role in the diagnosis, risk assessment and treatment of cardiovascular diseases..
