The proportional hazards model: applications in epidemiology
The proportional hazards model: applications in epidemiology
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比例风险模型：在流行病学中的应用
DOI：
10.1080/03610927808827626
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发表时间：
1978
影响因子：
0.8
通讯作者：
N. Breslow
中科院分区：
文献类型：
--
作者：
N. Breslow
考克斯（1972）的比例危害失效时间模型已广泛用于临床试验分析，它也提供了流行病学相对危险度概念的一种优雅的形式化。当用于比较研究队列与外部对照人群的疾病经验时，它概括了标准化发病率比（SMR）和比例发病率比（PMR）的概念。对于从高危人群中回顾性抽样匹配的病例和对照组的研究，该模型为多个危险因素的回归分析提供了灵活的工具。
Cox's (1972) Proportioal hazards failure time model, already widely used in the analysis of clinical trials, also provides an elegant formalization of the epidemiologic concept of relative risk. When used to compare the disease experience of a study cohort with that of an external control population, it generalizes the notions of the standardized morbidity ratio (SMR) and the proportional morbidity ratio (PMR). For studies in which matched sets of cases and controls are sampled retrospectively from the population at risk, the model provides a flexible tool for the regression analysis of multiple risk factors.