Squamous cell carcinoma of the oral cavity, maxillary antrum and lip in a Zimbabwean population: A descriptive epidemiological study
Squamous cell carcinoma of the oral cavity, maxillary antrum and lip in a Zimbabwean population: A descriptive epidemiological study
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DOI：
10.1016/j.oraloncology.2005.07.011
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发表时间：
2006-02-01
期刊：
影响因子：
4.8
通讯作者：
Mahomva, L
中科院分区：
文献类型：
--
作者：
Chidzonga, MM;Mahomva, L
鳞状细胞癌约占口腔恶性肿瘤的90%。这项研究的目的是记录津巴布韦人群中口腔、上颌窦和唇部鳞状细胞癌的性别、年龄、亚部位分布和组织分化。本文回顾了1982年1月至1991年12月在津巴布韦哈拉雷中心医院和Parirenyatwa医院就诊的口腔、上颌窦和唇部鳞状细胞癌患者的病历。口腔、上颌窦、鼻尖鳞状细胞癌占20.8%(n=358/1723)。年龄3-70岁，男女之比为2：1。男女发病高峰在41~50岁和51~60岁年龄组。亚位分布依次为下颌牙龈18.4%，舌17.9%，口底16.2%，上颌牙龈9.2%，颊粘膜9.2%，上颌窦12.6%，硬腭7.8%，软腭4.8%，下尖2.8%，上唇1.1%。64.8%为高分化，24.8%为中分化，10.4%为低分化。受累最多的是下颌牙龈、口底和舌头。嘴唇鳞状细胞癌并不常见。高分化鳞状细胞癌在41-60岁年龄组中最常见。(C)2005爱思唯尔有限公司。保留所有权利。
Squamous cell carcinoma accounts for approximately 90% of oral malignancies. The objective of this study was to document the gender, age, sub-site distribution and histologic differentiation of squamous cell carcinoma of the oral cavity, maxillary antrum and lip in a Zimbabwean population. Hospital records of patients with a histologic diagnosis of squamous cell carcinoma of the oral cavity, maxillary antrum and lip seen at Harare Central Hospital and Parirenyatwa Hospital in Zimbabwe during the period January 1982-December 1991 were reviewed. 20.8% (n = 358/1723) were squamous cell carcinoma of the oral cavity, maxillary antrum and tip. Age ranged from 3 to 70 years with a 2:1 male:female ratio. Peak incidence in both sexes were in the 41-50 and 51-60 years age groups. Sub-site distribution was mandibular gingiva 18.4%, tongue 17.9%, floor of the mouth 16.2%, maxillary gingiva 9.2%, buccal mucosa 9.2%, maxillary antrum 12.6%, hard palate 7.8%, soft palate 4.8%, lower tip 2.8% and upper lip 1.1%. 64.8% were well differentiated, 24.8% moderately differentiated and 10.4% poorly differentiated. The mandibular gingiva, floor of the mouth and tongue were most commonly affected. Lip squamous cell carcinoma was uncommon. Well-differentiated squamous cell carcinoma was most common in the 41-60 years age group. (c) 2005 Elsevier Ltd. All rights reserved.