Supplemental effect of cholyltaurine and soybean lecithin to a soybean meal-based fish meal-free diet on hepatic and intestinal morphology of rainbow trout Oncorhynchus mykiss
Supplemental effect of cholyltaurine and soybean lecithin to a soybean meal-based fish meal-free diet on hepatic and intestinal morphology of rainbow trout Oncorhynchus mykiss
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DOI：
10.1111/j.1444-2906.2008.01628.x
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发表时间：
2008-10-01
影响因子：
1.9
通讯作者：
Goto, Takanobu
中科院分区：
文献类型：
--
作者：
Iwashita, Yasuro;Suzuki, Nobuhiro;Goto, Takanobu
研究了在以脱脂豆粕为基础的无鱼粉饲料中添加胆酰牛磺酸和大豆卵磷脂对虹鳟（Oncorhynchus mykiss）肝脏和肠道形态的影响。以鱼粉为基础的饮食（FM），三种无鱼粉饮食补充大豆卵磷脂（SL），牛胆粉（BG）或胆酰牛磺酸（C-tau）和未补充的无鱼粉饮食（NFM），给鱼（类似于11 g）10周。在饲喂饲料NFM的鱼中生长最低，在饲喂饲料SL的鱼中生长居中，并且在饲喂饲料FM、BG和C-tau的鱼中生长最高。摄食NFM饲料的鱼肝细胞萎缩，这些鱼的远端肠道表现出异常特征：上皮细胞中的微绒毛和脂肪变性解体，粘膜下层中的结缔组织数量增加。饲喂SL、BG和C-tau的鱼的肝脏和肠道组织学特征与饲喂FM的鱼相似。这些结果表明，大豆卵磷脂，牛胆汁酸盐和胆酰牛磺酸具有类似的效果，正常的肝脏和肠道形态的虹鳟鱼喂养的SBM为基础的饮食，虽然生长促进作用是有限的大豆卵磷脂。
The supplemental effects of cholyltaurine and soybean lecithin to a defatted soybean meal (SBM)-based fish meal-free diet on the hepatic and intestinal morphology of rainbow trout Oncorhynchus mykiss were investigated. A fish meal-based diet (FM), three fish meal-free diets supplemented either with soybean lecithin (SL), bovine gall powder (BG) or cholyltaurine (C-tau) and an unsupplemented fish meal-free diet (NFM), were given to fish (similar to 11 g) for 10 weeks. The growth was the lowest in fish fed diet NFM, intermediate in fish fed diet SL and the highest in fish fed diet FM, BG and C-tau. Hepatocytes of fish fed diet NFM were atrophied, and the distal intestine of these fish showed abnormal features: disintegrated microvilli and fatty degeneration in epithelial cells and increased amount of connective tissue in the submucosa. Hepatic and intestinal histological features in fish fed diets SL, BG and C-tau were similar to those in fish fed diet FM. These results indicate that soybean lecithin, bovine bile salts and cholyltaurine have similar effects on normalizing the hepatic and intestinal morphologies of rainbow trout fed the SBM-based diet, although growth promotion effect was limited in the soybean lecithin.