Targeted memory reactivation of face-name learning depends on ample and undisturbed slow-wave sleep
Targeted memory reactivation of face-name learning depends on ample and undisturbed slow-wave sleep
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DOI：
10.1101/2021.02.16.431530
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发表时间：
2021-02
影响因子：
4.2
通讯作者：
N. Whitmore;Adrianna M. Bassard;K. Paller
中科院分区：
文献类型：
--
作者：
N. Whitmore;Adrianna M. Bassard;K. Paller
面部记忆，包括回忆一个人的名字的能力，在社交环境中非常重要。与许多其他记忆功能一样，它可能依赖于睡眠。我们研究了睡眠期间有针对性的记忆重新激活是否可以改善面部记忆的联想和感知方面。参与者研究了 80 对面孔名称，然后在白天小睡期间以不引人注目的方式呈现一组带有相关背景音乐的口语名称。这种操作优先改善了那些重新激活的面孔-姓名对的姓名回忆和面孔识别，并受到与睡眠质量相关的两个因素的调节；记忆益处与 N3 阶段睡眠（慢波睡眠）的持续时间呈正相关，与睡眠中断的测量呈负相关。我们的结论是（a）在睡眠期间重新激活特定的面孔记忆可以加强这些关联和构成记忆，并且（b）这种重新激活的有效性取决于不间断的 N3 睡眠。
Face memory, including the ability to recall a person’s name, is of major importance in social contexts. Like many other memory functions, it may rely on sleep. We investigated whether targeted memory reactivation during sleep could improve associative and perceptual aspects of face memory. Participants studied 80 face-name pairs, and then a subset of spoken names with associated background music was presented unobtrusively during a daytime nap. This manipulation preferentially improved name recall and face recognition for those reactivated face-name pairs, as modulated by two factors related to sleep quality; memory benefits were positively correlated with the duration of stage N3 sleep (slow-wave sleep) and negatively correlated with measures of sleep disruption. We conclude that (a) reactivation of specific face-name memories during sleep can strengthen these associations and the constituent memories, and that (b) the effectiveness of this reactivation depends on uninterrupted N3 sleep.