Mortality in British vegetarians: results from the European Prospective Investigation into Cancer and Nutrition (EPIC-Oxford)
Mortality in British vegetarians: results from the European Prospective Investigation into Cancer and Nutrition (EPIC-Oxford)
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DOI：
10.3945/ajcn.2009.26736l
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发表时间：
2009-05-01
影响因子：
7.1
通讯作者：
Allen, Naomi E.
中科院分区：
文献类型：
--
作者：
Key, Timothy J.;Appleby, Paul N.;Allen, Naomi E.
背景资料：很少有前瞻性研究调查了素食者的死亡率。目的：我们介绍欧洲癌症与营养前瞻性调查中素食者和非素食者的死亡率结果（EPIC-Oxford）。设计：我们采用了一项前瞻性研究，在20世纪90年代在整个英国招募了男性和女性。在64，234名年龄在20-89岁的参与者中，已知饮食组，2965人在2007年6月30日之前死于90岁。参与者的死亡率远低于联合王国的平均水平。所有死亡原因的标准化死亡率为52%（95%CI：50%，54%），素食者和非素食者相同。在招募时没有心血管疾病或恶性肿瘤的47,254名参与者中，将素食者与肉食者进行比较，经年龄，性别，吸烟和饮酒调整后的死亡率比为0.81（95%CI：0.57，1.16）和1.03（95%CI：0.90，1.16）的所有死因。结论：无论是素食者和非素食者在这项研究中的死亡率是低的全国率相比。在这项研究中，循环系统疾病和所有原因的死亡率在素食者和肉食者之间没有显着差异，但这项研究还不足以排除特定死亡原因的微小或中等差异，需要对这一主题进行更多的研究。美国临床营养杂志2009; 89（增刊）：1613 S-9 S。
Background: Few prospective studies have examined the mortality of vegetarians.Objective: We present results on mortality among vegetarians and nonvegetarians in the European Prospective Investigation into Cancer and Nutrition (EPIC-Oxford).Design: We used a prospective study of men and women recruited throughout the United Kingdom in the 1990s.Results: Among 64,234 participants aged 20-89 y for whom diet group was known, 2965 had died before age 90 by 30 June 2007. The death rates of participants are much lower than average for the United Kingdom. The standardized mortality ratio for all causes of death was 52% (95% CI: 50%, 54%) and was identical in vegetarians and in nonvegetarians. Comparing vegetarians with meat eaters among the 47,254 participants who had no prevalent cardiovascular disease or malignant cancer at recruitment, the death rate ratios adjusted for age, sex, smoking, and alcohol consumption were 0.81 (95% CI: 0.57, 1.16) for ischemic heart disease and 1.03 (95% CI: 0.90, 1.16) for all causes of death.Conclusions: The mortality of both the vegetarians and the nonvegetarians in this study is low compared with national rates. Within the study, mortality from circulatory diseases and all causes is not significantly different between vegetarians and meat eaters, but the study is not large enough to exclude small or moderate differences for specific causes of death, and more research on this topic is required. Am J Clin Nutr 2009; 89(suppl): 1613S-9S.