Ultrasound measurements on os calcis: Precision and age-related changes in a normal female population
Ultrasound measurements on os calcis: Precision and age-related changes in a normal female population
复制标题
钙骨超声测量：正常女性群体的精确度和年龄相关变化
作者：
A. Schott;D. Hans;E. Sornay‐Rendu;P. Delmas;P. Meunier
我们对512名健康女性的跟骨进行了超声测量。宽带超声衰减（BUA）和声速（SOS），获得了月球阿基里斯超声仪器。研究对象是一组67名在我院工作的妇女（A组）和两组，这两组是两个大型前瞻性队列研究的一部分（B和C组）。B组由从一家大型保险公司随机挑选的244名年龄在31-79岁之间的妇女组成，C组由从选民名册中随机挑选的201名年龄在74-91岁之间的妇女组成。B组采用Hologic QDR 2000，C组采用Lunar DPX Plus，对股骨颈和全身进行双能X线吸收测量（DXA）。通过连续45天每天测量体模估计的Achilles体外精度，BUA为0.84%，SOS为0.12%。我们评估了在医院工作的20名健康志愿者的体内短期精度，每人测量三次。BUA和SOS的变异系数分别为0.93%（±0.21）和0.15%（±0.03）。将精密度误差与真实变异进行比较，以获得标准化变异系数。我们分析了三组合并在一起（n=512），发现BUA平均下降20%，SOS下降5%，年龄在20至90岁之间。我们还对50岁以下和50岁以上的受试者进行了单独分析，在每个10岁年龄组中，我们发现BUA从20岁到50岁稳定或略有增加，然后在50岁后下降。相比之下，SOS没有增加，但从20岁开始下降。我们比较了B组和C组的股骨颈和全身DXA测量值与超声测量值。在两组中，全身DXA的相关性优于股骨颈和脊柱DXA。
We performed ultrasound measurements in the calcaneus of 512 healthy women. Broadband ultrasonic attenuation (BUA) and speed of sound (SOS) were obtained with a Lunar Achilles ultrasonic instrument. Subjects studied were one group of 67 women working in our hospital (group A) and two groups which are part of two large prospective cohort studies (groups B and C). Group B consisted of 244 women aged 31–79 years randomly selected from a large insurance company, and group C consisted of 201 women aged 74–91 years randomly selected from the electoral rolls. Dual-energy X-ray absorptiometry (DXA) measurements of femoral neck and total body were performed with a Hologic QDR 2000 for group B and with a Lunar DPX Plus for group C. The in vitro precision of the Achilles, estimated by measuring a phantom daily for 45 days, was 0.84% for BUA and 0.12% for SOS. We assessed the in vivo short-term precision in 20 healthy volunteers working at the hospital, measured three times each. The coefficients of variation were 0.93% (±0.21) for BUA and 0.15% (±0.03) for SOS. The precision error was compared with the true variation, to obtain a standardized coefficient of variation. We analysed the three groups pooled together (n=512) and found for BUA an average 20% decrease and for SOS a 5% decrease between the ages of 20 and 90 years. We also performed separate analyses of subjects younger than 50 and older than 50 years, and within each 10-year age group we found that BUA was stable or slightly increased from 20 to 50 years and then decreased after 50. In contrast, SOS did not increase but decreased from the age of 20. We compared DXA measurements of the femoral neck and the total body with ultrasound measurements in groups B and C. In both groups the correlations were better with total body DXA than with femoral neck and spine DXA.
四肢骨密度和年龄可预测女性髋部骨折。
DOI：
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发表时间：
1990
期刊：
JAMA : the journal of the American Medical Association
影响因子：
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作者：
Cummings,SR;Black,DM;Nevitt,MC;Browner,WS;Cauley,JA;Genant,HK;Mascioli,SR;Scott,JC;Seeley,DG;Steiger,P
通讯作者：
Steiger,P