Improvement in GOS and GOSE scores 6 and 12 months after severe traumatic brain injury
Improvement in GOS and GOSE scores 6 and 12 months after severe traumatic brain injury
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DOI：
10.1080/02699050701727460
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发表时间：
2007-11-01
期刊：
影响因子：
1.9
通讯作者：
Garcia-Huete, Lucia
中科院分区：
文献类型：
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作者：
Corral, Luisa;Luis Ventura, Jose;Garcia-Huete, Lucia
主要目的：评估严重创伤性脑损伤（TBI）后6个月至1年内格拉斯哥结局量表（GOS）和GOS扩展评分（GOSE）的改善情况。方法和程序：一项研究了214例格拉斯哥昏迷评分(GCS) < 9的重症监护病房（ICU）住院的严重TBI成年患者。195例受试者在伤后6、12个月分别进行GOS评分。患者以男性为主（84%），中位年龄为35岁。主要结局与结果：入院时GCS评分高组（6-8分）预后（6个月和1年GOS和GOSE）优于评分低组（3-5分）。入院时GCS评分高的组6个月至1年GOS评分的改善大于评分低的组。6个月时，75名患者死亡，120名患者存活。6-12个月评估期间无患者死亡；12个月时，36%的患者GOS评分改善。结论：36%的幸存者在严重TBI后6-12个月内GOS评分有所改善，结论是6个月时预期改善不完全。入院时GCS评分较好的患者（6-8）比GCS评分较差的患者（3-5）改善更大。
Primary objective: To assess improvements in Glasgow Outcome Scale (GOS) and GOS extended (GOSE) scores between 6 months and 1 year following severe traumatic brain injury (TBI).Methods and procedures: One studied 214 adult patients with severe TBI with Glasgow Coma Scale (GCS) < 9 admitted to Intensive Care Unit (ICU). GOS scores were obtained 6 and 12 months after injury in 195 subjects. Patients were predominantly male (84%) and median age was 35 years.Main outcomes and results: Outcome (GOS and GOSE at 6 months and I year) was better in the high GCS score at admission (6-8) group than in the low score group (3-5). The improvement in GOS scores between 6 months and 1 year was greater in the high GCS score at admission group than in the low score group. At 6 months, 75 patients had died and 120 survived. None died between the 6-12-month assessments; at 12 months, 36% had improved GOS score.Conclusions: GOS scores improved between 6-12 months after severe TBI in 36% of survivors and it is concluded that the expectancy of improvement is incomplete at 6 months. This improvement was greater in patients with better GCS scores (6-8) at admission than in those with worse GCS scores (3-5).