Self-administering cannabinoids.

Self-administering cannabinoids.
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自行施用大麻素。

DOI:
10.1016/j.tins.2005.05.001
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发表时间:
2005
期刊:
Trends in neurosciences.
影响因子:
--
通讯作者:
Scanziani,Massimo
Scanziani,Massimo
中科院分区:
--
文献类型:
--
作者:
Glickfeld,LindseyL;Scanziani,Massimo

文献摘要

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Endocannabinoids, which are typically released by principal cells in response to prolonged depolarization, act as retrograde messengers to inhibit synaptic transmission. A recent study shows that in a specific subtype of cortical interneuron, endocannabinoids released under similar circumstances can also act cell-autonomously. Here, endocannabinoids endow these neurons with a memory of their own activity in the form of a long-term change in excitability.