The DNA sequence of equine herpesvirus-4
The DNA sequence of equine herpesvirus-4
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DOI：
10.1099/0022-1317-79-5-1197
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发表时间：
1998-05-01
影响因子：
3.8
通讯作者：
Davison, AJ
中科院分区：
文献类型：
--
作者：
Telford, EAR;Watson, MS;Davison, AJ
测定了马疱疹病毒4型（EHV-4）NS 80567株的全基因序列。基因组大小为145 597 bp，由一个长的独特区域组成（U-L，112 398 bp）通过短反向重复排列（TRL/IRL，27 bp）连接到一个短的独特区域（U-S，12789 bp）通过大量反向重复排列（TRS/IRS，10178 bp），预测EHV-4含有76个不同的基因;其中三个在TRS/IRS中存在两次，总共有79个基因。密切相关的病毒马疱疹病毒-1（EHV-1）也具有与EHV-4对应的76个不同基因，但总共有80个基因，因为其中4个基因在TFS/IRS中存在两次。通过比较完整的DNA序列，对EHV-4和EHV-1基因组的编码能力进行了解释。
The complete DNA sequence of equine herpesvirus-4 (EHV-4) strain NS80567 was determined. The genome is 145 597 bp in size and consists of a long unique region (U-L, 112 398 bp) Ranked by a short inverted repeat (TRL/IRL, 27 bp) linked to a short unique region (U-S, 12789 bp) Ranked by a substantial inverted repeat (TRS/IRS, 10178 bp), EHV-4 is predicted to contain 76 different genes; three of these are present twice in TRS/IRS, giving a total of 79 genes. The closely related virus equine herpesvirus-1 (EHV-1) also possesses 76 different genes corresponding to those of EHV-4, but has a total of 80 genes because four are present twice in TFS/IRS,. Interpretations of the coding capacity of the EHV-4 and EHV-1 genomes were refined by comparing the complete DNA sequences.