Cranberry-containing products are associated with a protective effect against urinary tract infections.
Cranberry-containing products are associated with a protective effect against urinary tract infections.
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DOI：
10.1136/eb-2012-100984
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发表时间：
2013-06
期刊：
影响因子：
--
通讯作者：
Stapleton AE
中科院分区：
文献类型：
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作者：
Stapleton AE
方法遵循PRISMA指南进行系统评价。两位作者检索了MEDLINE，并手动检索了比较蔓越莓产品与安慰剂或非安慰剂对照预防UTI的随机对照试验，报告结果为UTI的发生率。四位作者对研究类型和设计、研究人群特征、干预和对照、UTI定义、结局和受试者失访进行了数据提取和质量评估。分析工具为科克伦偏倚风险工具R2。11.1统计软件，Galbraith和漏斗图。进行风险比、异质性检验、随机效应汇总估计、敏感性分析和亚组分析。
MethodsThis systematic review followed PRISMA guidelines. Two authors searched MEDLINE and manually searched for randomised controlled trials comparing cranberry products versus placebo or non-placebo control, for prevention of UTI, reporting outcomes as incidence of UTI. Four authors conducted data extraction and quality assessment of type of study and design, study population characteristics, interventions and controls, UTI definition, outcomes and subject loss to follow-up. Analysis tools were Cochrane risk of bias tool, R2. 11.1 statistical software, Galbraith and funnel plots. Risk-ratios, tests of heterogeneity, random effects summary estimates, sensitivity analyses and subgroup analyses with metaregression were performed.