SELF-ASSEMBLY THROUGH HYDROGEN-BONDING - PREPARATION AND CHARACTERIZATION OF 3 NEW TYPES OF SUPRAMOLECULAR AGGREGATES BASED ON PARALLEL CYCLIC CA3.M3 ROSETTES
SELF-ASSEMBLY THROUGH HYDROGEN-BONDING - PREPARATION AND CHARACTERIZATION OF 3 NEW TYPES OF SUPRAMOLECULAR AGGREGATES BASED ON PARALLEL CYCLIC CA3.M3 ROSETTES
复制标题
DOI：
10.1021/ja00084a013
复制
发表时间：
1994-03-09
影响因子：
15
通讯作者：
WHITESIDES, GM
中科院分区：
文献类型：
--
作者：
MATHIAS, JP;SETO, CT;WHITESIDES, GM
HUB(MM)(3)是一种含有六种三聚氰胺的化合物，它与异氰尿酸的单体、二聚体和三聚体衍生物反应，产生了三种新型的氢键自组装超分子聚集体。这些新的聚集体由Hub(MM)(3)：3benz(CA)(2)和Hub(MM)(3)：3呋喃(CA)(2)、Hub(MM)(3)：6new hex(CA)和Hub(MM)(3)：3new hex(CA)：C(18)Hub(CA)(3)表示。这些超分子聚集体由4-7个单独的分子组成，分子量在4.1-6.3 kDa之间。每个聚集体由两个平行循环CA(3)·M(3)的36个氢键稳定。通过H-1和C-13核磁共振波谱、凝胶渗透层析和蒸汽压渗透仪对这些聚集体进行表征，证实每个聚集体在氯仿或二氯甲烷溶液中都以稳定、明确的结构存在。讨论了这些自组装聚集体的设计、它们的相对稳定性以及用于表征它们的技术。证明了正协作性在HUB(MM)(3)：6新六角(CA)自组装中的操作。Hub(MM)(3)：3new hex(CA)：C(18)Hub(CA)(3)的自组装证明了三种不同组分的可控聚集成单一的超分子聚集体。这些自组装聚集体的大小和稳定性与凝胶渗透层析的结果相关联。
Reaction of hub(MM)(3), a compound containing six melamines, with monomeric, dimeric, and trimeric derivatives of isocyanuric acid yields three new types of hydrogen-bonded self-assembled supramolecular aggregates. These new aggregates are represented by hub(MM)(3):3benz(CA)(2) and hub(MM)(3):3furan(CA)(2), hub(MM)(3):6neohex(CA), and hub(MM)(3):3neohex(CA):C(18)hub(CA)(3). These supramolecular aggregates comprise 4-7 individual molecules and have molecular weights in the range 4.1-6.3 kDa. Each aggregate is stabilized by 36 hydrogen bonds in two parallel cyclic CA(3).M(3) ''rosettes''. Characterization of these aggregates by H-1 and C-13 NMR spectroscopies, gel permeation chromatography, and vapor pressure osmometry confirms that each exists as a stable, well-defined structure in chloroform or methylene chloride solutions. The design of these self-assembled aggregates, their relative stabilities,and the techniques used for their characterization are discussed. The operation of positive cooperativity in the self-assembly of hub(MM)(3):6neohex(CA) is demonstrated. The self-assembly of hub(MM)(3):3neohex(CA):C(18)hub(CA)(3) demonstrates the controlled aggregation of three different components into a single supramolecular aggregate. The size and stability of these self-assembled aggregates are correlated with results obtained from gel permeation chromatography.