High frequency oscillations in the intact brain.

High frequency oscillations in the intact brain.
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DOI:
10.1016/j.pneurobio.2012.02.004
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发表时间:
2012-09
影响因子:
6.7
通讯作者:
Silva FL
Silva FL
中科院分区:
医学2区
文献类型:
--
作者:
Buzsáki G;Silva FL

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高频振荡(HFO)构成了神经生理学的一个新趋势,它吸引了神经学家,特别是癫痫学家。但什么是HFO呢?高频振荡的频率范围是多少?有不同类型的HFO,生理性的和病理性的?HFO是如何产生的?HFO能代表认知过程的时间代码吗?这些问题迫在眉睫,这本研讨会卷试图给出建设性的答案。作为这一激动人心的讨论的前奏,我们总结了完整大脑中的生理高频模式,主要集中在海马区模式,在那里高频振荡的机制可能是最好的理解。
High frequency oscillations (HFOs) constitute a novel trend in neurophysiology that is fascinating neuroscientists in general, and epileptologists in particular. But what are HFOs? What is the frequency range of HFOs? Are there different types of HFOs, physiological and pathological? How are HFOs generated? Can HFOs represent temporal codes for cognitive processes? These questions are pressing and this symposium volume attempts to give constructive answers. As a prelude to this exciting discussion, we summarize the physiological high frequency patterns in the intact brain, concentrating mainly on hippocampal patterns, where the mechanisms of high frequency oscillations are perhaps best understood.