Particulate bioglass(R) as a grafting material in the treatment of periodontal intrabony defects
Particulate bioglass(R) as a grafting material in the treatment of periodontal intrabony defects
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DOI：
10.1111/j.1600-051x.1997.tb00205.x
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发表时间：
1997-06-01
影响因子：
6.7
通讯作者：
Newman, HN
中科院分区：
文献类型：
--
作者：
Zamet, JS;Darbar, UR;Newman, HN
本临床试验旨在评估生物活性玻璃Perioglas（R）在治疗牙周骨内缺损中的效果。20名年龄在23-55岁（44个部位）的骨内缺损患者完成了1年研究。根分叉病变的牙齿被排除。完成初始治疗后，缺陷被随机分配到测试或对照程序。在两组中进行皮瓣反射、根面平整和去除慢性炎症组织后，用生物活性玻璃颗粒材料修复测试缺损。粘骨膜瓣被替换，缝合和牙周敷料的使用。所有患者均接受术后抗生素和镇痛药治疗，并在1周时进行缝线拆除。然后每周以及术后3个月、6个月、9个月和1年进行随访。记录基线、3个月和1年时的菌斑评分、出血评分、牙周袋探诊深度（PPD）、牙周袋探诊附着水平（PAL）和牙龈退缩情况。在基线、术后即刻和1年时拍摄用于计算机辅助密度图像分析（CADIA）的标准化X线片。CADIA数据显示显著增加（F-比率：15.67，p
The present clinical trial was designed to evaluate the effects of a bioactive glass, Perioglas(R), in the treatment of periodontal intrabony defects. 20 patients, 23-55 years of age (44 sites), with intrabony defects completed the 1-year study. Teeth with furcation involvement were excluded. After completion of initial therapy, defects were randomly assigned to either a test or control procedure. Following flap reflection, root planing and removal of chronic inflammatory tissue in both groups, the test defects were restored with the bioactive glass particulate material. Mucoperiosteal flaps were replaced, sutured and a periodontal dressing was used. All the patients received postoperative antibiotics and analgesics and were seen at 1 week for suture removal. Follow-up was then carried out weekly and at 3 months, 6 months, 9 months and 1 year post-surgery. Plaque score, bleeding score, probing pocket depth (PPD), probing attachment level (PAL) and gingival recession were recorded at baseline, 3 months and 1 year. Standardised radiographs for computer-assisted densitometric image analysis (CADIA) were taken at baseline, immediately post-operatively and at 1 year. The CADIA data showed a significant increase (F-ratio: 15.67, p