White rice ethanol extract is qualitatively, but not quantitatively, equivalent to that of brown rice as an antioxidant source
White rice ethanol extract is qualitatively, but not quantitatively, equivalent to that of brown rice as an antioxidant source
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DOI：
10.1093/bbb/zbab133
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发表时间：
2021-07-19
影响因子：
1.6
通讯作者：
Nakamura，Yoshimasa
中科院分区：
文献类型：
--
作者：
Wu，Hongyan;Nakamura，Toshiyuki;Nakamura，Yoshimasa
这项研究的目的是比较白米(WR)和糙米(BR)在体外试验和细胞模型中展示生物活性抗氧化作用的潜力。对于1，1-二苯基-2-苦基肼分析，WR每1mg乙醇提取物的特罗克斯当量(TE)略高于BR，但每1g WR的TE值远低于BR。这一趋势与氧自由基吸收能力和总多酚含量的变化非常相似。两种乙醇提取物也同样抑制过氧化氢诱导的细胞毒性，并增强药物代谢酶的基因表达。基于α-生育酚的含量，其对大米提取物的细胞保护作用的贡献是非常有限的。综上所述，WR的乙醇提取物在性质上可能是与BR相同的抗氧化植物化学物质的来源，但在数量上不是相同的。
The purpose of this study is to compare the potentials to exhibit biologically active antioxidant actions between white rice (WR) and brown rice (BR) inin vitroassays and a cellular model. The Trolox equivalent (TE) per 1 mg ethanol extract of WR for the 1,1-diphenyl-2-picrylhydrazyl assay was slightly higher than that of BR, whereas the TE per 1 g whole WR was much lower than that for BR. This tendency was very comparable to those for the oxygen radical absorbance capacity and total polyphenol content. Both of the ethanol extracts also similarly suppressed the hydrogen peroxide-induced cytotoxicity and enhanced the gene expression of drug-metabolizing enzymes. Based on the α-tocopherol quantity, its contribution to the cytoprotective effect of the rice extracts is very limited. Taken together, the ethanol extract of WR might be a qualitatively, but not quantitatively, equivalent source of antioxidative phytochemicals to that of BR.