'To prove this is the industry's best hope': big tobacco's support of research on the genetics of nicotine addiction
'To prove this is the industry's best hope': big tobacco's support of research on the genetics of nicotine addiction
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DOI：
10.1111/j.1360-0443.2010.02940.x
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发表时间：
2010-06-01
期刊：
影响因子：
6
通讯作者：
Koenig, Barbara A.
中科院分区：
文献类型：
--
作者：
Gundle, Kenneth R.;Dingel, Molly J.;Koenig, Barbara A.
背景新的分子技术将遗传视角聚焦于尼古丁成瘾。考虑到与吸烟相关的医疗和经济成本，必须寻求创新的戒烟和预防方法；但烟草业可以操纵合理的研究吗？方法论本文的时间顺序叙述是通过对主要来源（遗留烟草文件）的迭代审查而创建的，并辅以二手文献以提供更广泛的背景。这些实证数据为烟草业资助的研究的伦理和政策分析提供了信息。调查结果对吸烟遗传基础的探索与烟草业数十年来将责任从烟草公司转移到个人基因构成上的计划是一致的。内部文件显示，长期以来对基因研究的支持，将其作为减轻烟草业对烟草相关疾病的法律责任的战略。结论烟草业可能会利用遗传学的发现来达到自己的目的，将战略从创造“安全”卷烟转变为定义“安全”吸烟者。
BackgroundNew molecular techniques focus a genetic lens upon nicotine addiction. Given the medical and economic costs associated with smoking, innovative approaches to smoking cessation and prevention must be pursued; but can sound research be manipulated by the tobacco industry?MethodologyThe chronological narrative of this paper was created using iterative reviews of primary sources (the Legacy Tobacco Documents), supplemented with secondary literature to provide a broader context. The empirical data inform an ethics and policy analysis of tobacco industry-funded research.FindingsThe search for a genetic basis for smoking is consistent with industry's decades-long plan to deflect responsibility away from the tobacco companies and onto individuals' genetic constitutions. Internal documents reveal long-standing support for genetic research as a strategy to relieve the tobacco industry of its legal responsibility for tobacco-related disease.ConclusionsIndustry may turn the findings of genetics to its own ends, changing strategy from creating a 'safe' cigarette to defining a 'safe' smoker.