The inactivation of resistant Candida albicans in a sealed package by cold atmospheric pressure plasmas

The inactivation of resistant Candida albicans in a sealed package by cold atmospheric pressure plasmas
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DOI:
10.1002/ppap.201100075
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发表时间:
2012
影响因子:
3.5
通讯作者:
Yingde Song;Dongping Liu;Longfei Ji;Wenchun Wang;Pengchao Zhao;C. Quan;Jinhai Niu;Xianhui Zhang
Yingde Song;Dongping Liu;Longfei Ji;Wenchun Wang;Pengchao Zhao;C. Quan;Jinhai Niu;Xianhui Zhang
中科院分区:
物理与天体物理3区
文献类型:
--
作者:
Yingde Song;Dongping Liu;Longfei Ji;Wenchun Wang;Pengchao Zhao;C. Quan;Jinhai Niu;Xianhui Zhang

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在用于生物消毒的密封包装中产生冷的大气压等离子体仍然是一个挑战。在本文中,我们报告了一种等离子体装置,在密封包装中形成大面积和大气压等离子体,用于低温消毒真菌。在装有白色念珠菌的便携式塑料袋中,将105个孢子置于血浆装置上,容易产生目视均匀的血浆。含1%O_2的He等离子体对耐药白念珠菌作用时间为5min。光学发射光谱和消毒效率的测量表明,等离子体产生的物质(如O自由基和带电物质)在灭活过程中起主要作用。
It remains a challenge to generate cold, atmospheric pressure plasmas in sealed packages for biological disinfection. In this paper, we report a plasma device to form large‐area and atmospheric‐pressure plasmas in a sealed package for the low‐temperature disinfection offungi. The visually uniform plasmas were easily generated in the portable plastic bag containingCandida albicanswith a population of 105spores placed on the plasma device. The He plasma containing about 1% O2was found to entirely kill resistantCandida albicanswith a treatment time of 5 min. Measurements for optical emission spectra and disinfection efficiencies indicate that the plasma‐created species such as O radicals and charged species play a major role in the inactivation process.