TRAK ontology: Defining standard care for the rehabilitation of knee conditions
TRAK ontology: Defining standard care for the rehabilitation of knee conditions
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DOI：
10.1016/j.jbi.2013.04.009
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发表时间：
2013-08-01
影响因子：
4.5
通讯作者：
Spasic, Irena
中科院分区：
文献类型：
--
作者：
Button, Kate;van Deursen, Robert W.;Spasic, Irena
在本文中，我们讨论了TRAK（膝关节康复分类法）的设计和开发，这是一个正式建模膝关节康复相关信息的本体。TRAK提供了一个框架，可用于收集足够详细的编码数据，以支持流行病学研究，从而可以确定最有效的治疗成分，开发新的干预措施，并提高未来随机对照试验的质量，以纳入定义明确并反映临床实践的对照干预措施。TRAK遵循开放生物医学本体（OBO）铸造厂推荐的设计原则。TRAK使用基本形式本体（Basic Formal Ontology， BFO）作为上层本体，并参考其他相关本体，如信息工件本体（Information Artifact Ontology， IAO）、普通医学本体（Ontology for General Medical Science， OGMS）和表型与特征本体（Phenotype and Trait Ontology， PATO）。TRAM与其他生物本体正交，代表了膝关节康复中使用的治疗和模式的领域特定知识。作为治疗方式的典型练习的定义提供了适当的插图，可以在OBO-Edit本体编辑器中查看。TRAM中的绝大多数其他类都与统一医学语言系统（UMLS）交叉引用，以方便将来与其他术语源的集成。TRAM是在OBO中实现的，这是OBO社区广泛使用的一种格式。电车可从http://www.cs.cf.ac.uk/trak下载。此外，它的公开发布可以通过生物门户网站访问，在那里它可以浏览，搜索和可视化。(C) 2013爱思唯尔公司版权所有。
In this paper we discuss the design and development of TRAK (Taxonomy for RehAbilitation of Knee conditions), an ontology that formally models information relevant for the rehabilitation of knee conditions. TRAK provides the framework that can be used to collect coded data in sufficient detail to support epidemiologic studies so that the most effective treatment components can be identified, new interventions developed and the quality of future randomized control trials improved to incorporate a control intervention that is well defined and reflects clinical practice. TRAK follows design principles recommended by the Open Biomedical Ontologies (OBO) Foundry. TRAK uses the Basic Formal Ontology (BFO) as the upper-level ontology and refers to other relevant ontologies such as Information Artifact Ontology (IAO), Ontology for General Medical Science (OGMS) and Phenotype And Trait Ontology (PATO). TRAM is orthogonal to other bio-ontologies and represents domain-specific knowledge about treatments and modalities used in rehabilitation of knee conditions. Definitions of typical exercises used as treatment modalities are supported with appropriate illustrations, which can be viewed in the OBO-Edit ontology editor. The vast majority of other classes in TRAM are cross-referenced to the Unified Medical Language System (UMLS) to facilitate future integration with other terminological sources. TRAM is implemented in OBO, a format widely used by the OBO community. TRAM is available for download from http://www.cs.cf.ac.uk/trak. In addition, its public release can be accessed through BioPortal, where it can be browsed, searched and visualized. (C) 2013 Elsevier Inc. All rights reserved.