Prevalence of nosocomial infections at intensive care units in Turkey: A multicentre 1-day point prevalence study
Prevalence of nosocomial infections at intensive care units in Turkey: A multicentre 1-day point prevalence study
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DOI：
10.1080/00365540410019156
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发表时间：
2004-02-01
影响因子：
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通讯作者：
Leblebicioglu, H
中科院分区：
文献类型：
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作者：
Esen, S;Leblebicioglu, H
为了确定土耳其重症监护病房(ICU)获得性感染的流行率，并确定相关的危险因素、主要感染生物体和死亡率，2001年9月19日进行了一项一维点流行率研究。来自22所大学和教学医院的56个ICU参加了调查，总共接受了236份填写好的病例报告表进行分析。ICU院内感染115例(48.7%)，肺炎和下呼吸道感染(28.0%)、实验室确诊的血液感染(23.3%)和尿路感染(15.7%)是最常见的感染类型。气管插管、留置导尿管、入院时多发伤、预防应激性溃疡、鼻饲、机械通气是高危因素。最常见的病原菌是铜绿假单胞菌(20.8%)、金黄色葡萄球菌(18.2%)、不动杆菌属。(18.2%)和克雷伯氏菌属。(16.1%)。在这些患者中，72.9%的患者在研究中接受了抗菌药的治疗或预防。最常见的抗菌药物是氨基糖苷类(37.2%)、碳青霉烯类(31.4%)、糖肽类(23.3%)、头孢菌素类(18.0%)和抗真菌药(5.8%)。随访4周，死亡70例(29.7%)，其中死于ICU相关感染22例(9.3%)。总之，这项研究表明，ICU相关感染很常见，而且往往与耐药微生物有关。研究结果提供了有助于在ICU实施感染控制政策的流行病学信息。
In order to determine the prevalence of intensive care unit (ICU)-acquired infection at ICUs in Turkey and to identify associated risk factors, predominant infecting organisms and mortality rates, a 1-d point prevalence study was carried out on 19 September 2001. A total of 56 ICUs from 22 university and teaching hospitals participated and a total of 236 completed case report forms were accepted for analyses. A total of 115 patients (48.7%) had 1 or more ICU-related nosocomial infections on the study d. Pneumonia and lower respiratory tract infection (28.0%), laboratory confirmed blood stream infection (23.3%) and urinary tract infection (15.7%) were the most frequent types. Endotracheal tube, urinary catheter, multi-trauma on admission, stress ulcer prophylaxis, nasogastric feeding and mechanical ventilation were risk factors. The most frequently reported isolates were Pseudomonas aeruginosa (20.8%), Staphylococcus aureus (18.2%), Acinetobacter spp. ( 18.2%) and Klebsiella spp. (16.1%). Of the patients, 72.9% were receiving antimicrobials on the study d for treatment or prophylaxis. Most frequently administered antimicrobials were aminoglycosides (37.2%), carbapenems (31.4%), glycopeptides ( 23.3%), cephalosporins (18.0%) and antifungals (5.8%). According to a 4-week follow-up, 70 (29.7%) patients died, 22 (9.3%) of whom died from ICU related infections. In conclusion this study showed that ICU related infections are common and often associated with resistant microorganisms. The results provide epidemiological information that will help to implement infection control policies in ICUs.