Oral Pemphigus Vulgaris Associated with Inflammatory Bowel Disease and Herpetic Gingivostomatitis in an 11‐Year‐Old Girl
Oral Pemphigus Vulgaris Associated with Inflammatory Bowel Disease and Herpetic Gingivostomatitis in an 11‐Year‐Old Girl
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一名 11 岁女孩口腔寻常型天疱疮与炎症性肠病和疱疹性龈口炎相关
作者：
J. Prendiville;D. Israel;W. Wood;J. Dimmick
摘要：1例新近诊断为口腔寻常型天疱疮的11岁女孩，由于重叠感染I型单纯疱疹病毒而发展为严重的口腔溃疡加重，同时诊断为慢性炎症性肠病，以解释体重减轻和间歇性血性腹泻的症状，这些症状早于口腔溃疡数年。单纯疱疹病毒感染是寻常型天疱疮公认的并发症，可能被误认为是疾病的复发。天疱疮与慢性炎症性肠病的关系已经在少数成年人中得到了证明。它与植物化脓性口炎的关系尚不清楚，化脓性口炎是溃疡性结肠炎和克罗恩病的公认标志。
Abstract: An 11‐year‐old girl with recently diagnosed oral pemphigus vulgaris developed a severe exacerbation of mouth ulceration due to superinfection with herpes simplex virus type I. A concurrent diagnosis of chronic inflammatory bowel disease was established to explain symptoms of weight loss and intermittent bloody diarrhea that predated the oral ulceration by several years. Herpes simplex infection is a recognized complication of pemphigus vulgaris that may be mistaken for a recrudescence of the disease. The association of pemphigus with chronic inflammatory bowel disease has been documented in a small number of adults. Its relationship to pyostomatitis vegetans, an acknowledged marker for ulcerative colitis and Crohn disease, remains unclear.