Indocyanine green for successful repair of a long-standing macular hole
Indocyanine green for successful repair of a long-standing macular hole
复制标题
DOI：
10.1016/s0002-9394(03)00200-9
复制
发表时间：
2003-08-01
影响因子：
4.2
通讯作者：
Kampik, A
中科院分区：
文献类型：
--
作者：
Haritoglou, C;Neubauer, AS;Kampik, A
方法：对1例陈旧性黄斑裂孔患者(18岁)行玻璃体切除联合内界膜剥离。第一次手术中不使用染料，第二次手术中使用0.05%ICG冲剂。在ICG涂抹后立即关闭光源，直到15秒后染料被洗掉。结果：第一次手术失败后，可用ICG对未完全剥离的ILM区域进行染色，彻底去除ILM。术后黄斑裂孔闭合，光学相干断层扫描证实。视力从20/200提高到20/50。术后均未见视野缺陷。结论：在未完全去除ILM的牵引力被认为是导致黄斑裂孔持续存在的原因的情况下，ICG有助于识别未剥离的ILM区域。在某些安全预防措施下，未发现对功能结果的不良影响。
METHODS: A patient with a long standing macular hole (18 years) underwent pars plana vitrectomy with peeling of the internal limiting membrane (ILM). While no dye was used during the first operation, ICG (0.05%, Pulsion) was applied during the second procedure. The light source was turned off immediately after the ICG application until the dye was washed out after a period of 15 seconds. Tissue harvested during the second surgical approach was prepared for electron microscopy.RESULTS: After the failure of the first operation, areas of incomplete ILM peeling could be stained using ICG and a thorough ILM removal was achieved. Postoperatively, the macular hole was closed, as confirmed by optical coherence tomography. Visual acuity increased from 20/200 to 20/50. No visual field defects were seen postoperatively. There were only few cellular elements adherent to the retinal surface of the ILM as seen during electron microscopy.CONCLUSION: In cases where tractional forces due to incomplete ILM removal are considered responsible for the persistence of a macular hole, ICG is useful to identify areas of unpeeled ILM. Under certain safety precautions no adverse effect on functional outcome was seen.