A biometric study of human basal metabolism
A biometric study of human basal metabolism
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DOI：
10.1073/pnas.4.12.370
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发表时间：
1918-01-01
影响因子：
11.1
通讯作者：
Benedict, FG
中科院分区：
文献类型：
--
作者：
Harris, JA;Benedict, FG
生理学：哈里斯和本尼迪克特生产减少约7.15，而在妇女减少约2.29卡路里每年。女人比男人小，产热也低。当新陈代谢随年龄增长而减少的情况用每公斤体重的卡路里或每平方米体表的卡路里来表示时，两性的结果几乎相同。过去有许多作者讨论过男女新陈代谢的差异问题，现在根据现有的大量数据重新加以考虑。平均每日（24小时）的基础热量生产的男性是1632卡路里，而女性是1349卡路里。因此，女性的平均日产热量比男性少约300卡路里。但是女人比男人小。如果用每千克体重产热量来校正体型，则136名男性的产热量为25.7卡路里，而103名女性的产热量为24.5卡路里，即每千克少1.2卡路里。根据杜波依斯身高-体重图表估计的每平方米体表产热量，男性平均每日产热量为925卡路里，而103名女性为850卡路里，少75卡路里。对男性和女性新陈代谢水平差异的最关键检验是本尼迪克特和埃姆斯的选择群体方法的修改和扩展。在新的方法中，几组妇女的控制值不是尽可能接近的身高和体重等男性的生理常数，而是根据考虑了所有男性现有数据中的身高、体重和年龄的方程确定的。分析表明，无论如何表达，美国妇女的新陈代谢低于男性，我们的研究结果表明，性别的分化在婴儿期不明显。他们没有证实Sond 6 n和Tigerstedt的结论，即男性和女性之间的差异往往随着年龄的增长而消失。相反，我们发现男性和女性的新陈代谢差异在整个成年生活期间都很明显。
PHYSIOLOGY: HARRIS AND BENEDICT production decreases about 7.15 while in women it decreases about 2.29 calories per year. Women are smaller than men and have a lower heat pro-duction. When the decrease in metabolism with age is expressed in calories per kilogram of body weight or in calories per square meter of body surface, the results for the two sexes are much more nearly identical. The problem of the difference in the metabolism of men and women, dealt with in the past by a number of writers, has been reconsidered on the basis of the larger series of data now available. The average daily (24 hours) basal heat production of men is 1632 calories whereas that of women is 1349 calories. Thus women have an average daily heat production about 300ca-lories less thanthat of men. But women are smaller than men. If correc-tion for body size be made by expressing heat productionin calories per kilo-gram of body weight, it is 25.7 calories in the 136 men as compared with 24.5 calories, or 1.2 calories per kilogram less, in the 103 women. On the basis of heat production per square meter of body surface as estimated by the Du Bois height-weight chart the men show an average daily heat production of 925 calories as compared with 850 calories, or 75 calories less, in the 103 women. The most critical test of the difference of men and women inthe level of metabolism is that furnished by a modification and extension of the selected group method of Benedict and Emmes. In the new method the con-trol values for the several groupsof womenare not the empiricalconstants for men of as nearly as possiblelike stature and body weightbut are determined from equations takinginto account stature, weightand agein all the available data for men. Analysis shows that, however expressed, the metabolism of American women is lower than that of the men, Our results show that the differentiation of the sexes is not evident in infancy. They do not confirm the conclusion of Sond6n and Tigerstedt that the difference between men and women tends to disappear with age. Instead we find the difference in the metabolism of men and women well-marked throughout the period of adult life.