Diagnosis of Helicobacter pylori infection in gastric mucosa by endoscopic features: A multicenter prospective study
Diagnosis of Helicobacter pylori infection in gastric mucosa by endoscopic features: A multicenter prospective study
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DOI：
10.1111/den.12031
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发表时间：
2013-09-01
影响因子：
5.3
通讯作者：
Ida, Kazunori
中科院分区：
文献类型：
--
作者：
Kato, Takahiro;Yagi, Nobuaki;Ida, Kazunori
背景与悉尼系统病理结果相对应的内镜特征尚未确定，慢性胃炎的内镜诊断尚未建立。为了建立诊断幽门螺杆菌（H.pylori）感染的胃粘膜内镜下的功能，前瞻性多中心研究carried out.Patients and MethodsTwenty-nine-seven登记的患者从24个设施之间2008年3月和2009年2月入组。内镜检查结果（常规结果和靛胭脂对比（IC）方法的结果）和诊断幽门螺杆菌感染的活检标本的显微镜观察之间的关联进行了研究，在身体和胃窦和他们的诊断准确性investigated.ResultsTwo百和75例进行了分析。胃体部和胃窦部幽门螺杆菌感染受试者工作特征（ROC）曲线下面积分别为0.811和0.707（P=0.006）。常规内镜下弥漫性发红、点状发红和粘膜肿胀以及靛胭脂造影剂（IC）检查胃区肿胀有助于诊断H.pylori感染。角部集合小静脉排列规则，胃底腺息肉，体部出血性糜烂和出血点，红条，糜烂（平的，凸起的，出血和出血点）结论胃粘膜H. pylori感染的内镜诊断以常规内镜和IC法为主，可能
BackgroundEndoscopic features corresponding to pathological findings in the Sydney System have not been identified, and endoscopic diagnosis of chronic gastritis has not yet been established. To establish the diagnosis of Helicobacter pylori (H.pylori) infection in gastric mucosa by endoscopic features, a prospective multicenter study was carried out.Patients and MethodsTwo hundred and ninety-seven registered patients from 24 facilities between March 2008 and February 2009 were enrolled. Association between endoscopic findings (conventional findings and indigocarmine contrast (IC) method findings) and diagnosis of H.pylori infection made by microscopic observation of biopsy specimens was investigated in the corpus and antrum and their diagnostic accuracies were investigated.ResultsTwo hundred and seventy-five patients were analyzed. The area under the receiver operating characteristic (ROC) curve for H.pylori infection of conventional endoscopy was 0.811 in thecorpus and 0.707 in the antrum (P=0.006). Evaluation of diffuse redness, spotty redness and mucosal swelling by conventional endoscopy and swelling of areae gastricae by the indigocarmine contrast (IC) method were useful for diagnosing H.pylori infection. Regular arrangement of collecting venules (RAC) in the angle, fundic gland polyposis, hemorrhagic erosion and bleeding spot in the corpus and red streaks, and erosions (flat, raised, hemorrhagic and bleeding spot) in the antrum may be used as diagnostic features suggesting negative H.pylori infection.ConclusionIt is suggested that endoscopic diagnosis of H.pylori infection in gastric mucosa by conventional endoscopy and the IC method is mostly possible.