The bacterial peptide N-formyl-met-leu-phe inhibits killing of Staphylococcus epidermidis by human neutrophils in fibrin gels

The bacterial peptide N-formyl-met-leu-phe inhibits killing of Staphylococcus epidermidis by human neutrophils in fibrin gels
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DOI:
10.4049/jimmunol.168.2.816
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发表时间:
2002-01-15
影响因子:
4.4
通讯作者:
Silverstein, SC
Silverstein, SC
中科院分区:
医学2区
文献类型:
--
作者:
Li, YM;Loike, JD;Silverstein, SC

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To study human neutrophil (polymorphonuclear leukocyte (PMN)) migration and killing of bacteria In an environment similar to that found in inflamed tissues in vivo, we have used fibrin gels. Fibrin gels (1500 mum thick) containing Staphylococcus epidermidis were formed in Boyden-type chemotaxis chambers. PLAIN migrated