Expression of members of the Saccharomyces cerevisiae hsp70 multigene family.
Expression of members of the Saccharomyces cerevisiae hsp70 multigene family.
复制标题
酿酒酵母 hsp70 多基因家族成员的表达。
作者：
M. Werner;E. Craig
酿酒酵母的hsp70多基因家族是一个复杂的多基因家族，由表现出复杂调控模式的成员组成。一些成员的表达是诱导后的热休克，而其他的表达被压抑。该家族的一些成员在指数增长期间表达。一个基因，SSA3，显示出一个不寻常的模式，在接近稳定期的表达。虽然大多数RNA的丰度降低，但SSA3 RNA水平显著增加。SSA3在缺乏腺苷酸环化酶活性的细胞中的组成性表达表明cAMP调节SSA3的表达。
The hsp70 multigene family of Saccharomyces cerevisiae is a complex multigene family, composed of members exhibiting complex patterns of regulation. Expression of some members is induced after a heat shock, whereas expression of others is repressed. Some members of the family are expressed during exponential growth. One gene, SSA3, shows an unusual pattern of expression during approach to stationary phase. While most RNAs decrease in abundance, SSA3 RNA levels dramatically increase. The constitutive expression of SSA3 in cells lacking adenylate cyclase activity suggests that cAMP modulates SSA3 expression.