Changes in muscle sympathetic nerve activity and calf blood flow during static handgrip exercise
Changes in muscle sympathetic nerve activity and calf blood flow during static handgrip exercise
复制标题
静态握力运动过程中肌肉交感神经活动和小腿血流量的变化
DOI：
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发表时间：
2004
期刊：
影响因子：
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通讯作者：
S. Iwase
中科院分区：
文献类型：
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作者：
M. Saito;T. Mano;S. Iwase
为探讨交感缩血管神经对静止肢体肌肉收缩时血流的作用，在静止握力（SHG）前、中、后2min，用显微神经摄影技术记录胫神经对小腿肌肉的交感神经活动（MSNA）。同时用应变式体积描记法测定小牛血流量（CBF）。在SHG期间，同一静息肢体MSNA增加，CBF减少和小腿血管阻力（CVR）增加同时发生。然而，CVR的增加在第二分钟的手握时，MSNA仍在增加。结果表明，SHG时CBF的减少反映了MSNA的增加，而SHG后期MSNA与CVR的分离可能与血管收缩引起的代谢变化有关。
SummaryTo test the function of sympathetic vascoconstrictor nerves on blood flow in resting limbs during static muscle contraction, muscle sympathetic nerve activity (MSNA) to the leg muscle was recorded from the tibial nerve microneurographically before, during and after 2 min of static handgrip (SHG). Simultaneously, calf blood flow (CBF) was measured by strain gauge plethysmography. An increase in MSNA, a decrease in CBF and an increase in calf vascular resistance (CVR) in the same resting limb occurred concomitantly during SHG. However, the increase in CVR was blunted in the second minute of handgrip when MSNA was still increasing. The results indicated that the decrease of CBF during SHG reflects the increase in MSNA, while the dissociation between MSNA and CVR at the later period of SHG may be related to metabolic change produced by the vasoconstriction.