THE DEVELOPMENT OF ACELLULARITY OF THE VERTEBRAL BONE OF THE JAPANESE MEDAKA, ORYZIAS-LATIPES (TELEOSTEI, CYPRINIDONTIDAE)
THE DEVELOPMENT OF ACELLULARITY OF THE VERTEBRAL BONE OF THE JAPANESE MEDAKA, ORYZIAS-LATIPES (TELEOSTEI, CYPRINIDONTIDAE)
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DOI：
10.1002/jmor.1051930304
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发表时间：
1987-09-01
影响因子：
1.5
通讯作者：
HALL, BK
中科院分区：
文献类型：
--
作者：
EKANAYAKE, S;HALL, BK
在脊椎动物中，一些硬骨鱼的骨骼是独一无二的，缺乏嵌入基质中的骨细胞。分泌这些脱细胞骨基质的细胞的命运尚未彻底研究。组织学和荧光显微镜分析的脊椎骨的Oryzias latipes表明，无细胞性是不是一个次要的外观早期细胞骨在个体发育。脊椎骨在整个发育过程中缺乏嵌入基质中的细胞。分泌骨基质的细胞不会被困在自己的分泌物中。相反，它们总是作为表面层保留在骨的外表面上。荧光显微镜观察四环素注射到生长中的鱼表明，骨只沉积成骨细胞内衬骨的外表面，没有沉积的骨发生在内表面。
Among vertebrates, some teleosts are unique in having bone which lacks osteocytes embedded in the matrix. The fate of cells that secrete the matrix of these acellular bones has not been investigated thoroughly. Histological and fluorescent microscopic analysis of the vertebral bone of Oryzias latipes demonstrated that acellularity is not a secondary appearance of an early cellular bone during ontogeny. Vertebral bone is devoid of cells embedded in the matrix throughout development. Cells that secrete bone matrix do not become trapped in their own secretion. Instead, they always remain as a surface layer over the outer surface of the bone. Fluorescent microscopic visualization of tetracycline injected into growing fish demonstrated that bone was only deposited by osteoblasts lining the outer surface of the bone; no deposition of bone took place on the inner surface.