Smectic polymer vesicles
Smectic polymer vesicles
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近晶聚合物囊泡
DOI：
10.1039/b907485f
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发表时间：
2009-01-01
期刊：
影响因子：
3.4
通讯作者：
Li, Min-Hui
中科院分区：
文献类型：
--
作者：
Jia, Lin;Cao, Amin;Li, Min-Hui
聚合物囊泡是由嵌段共聚两亲分子制成的稳定而结实的囊泡。嵌段共聚物化学设计的最新进展为创造具有不同精细结构、功能和几何形状的各种聚合物囊泡提供了令人兴奋的可能性。聚合物囊泡不仅构成了药物输送和微/纳米反应器的有用系统，而且为探索三维曲面上物质的有序性提供了一个无价的舞台。通过选择合适的液晶聚合物作为共聚物的一种成分，人们可以创造出具有近晶条纹的囊泡。球形拓扑上的近晶有序不可避免地具有拓扑缺陷(错位)，这些缺陷本身就是潜在的化学官能化的区别区域和囊泡萌发的成核因素。在这里，我们报告了由两亲嵌段共聚物形成的玻璃条纹聚合物囊泡，其中疏水嵌段是含有胆固醇基介晶的近晶液晶聚合物。囊泡呈二维近晶有序，呈椭圆形，两极有缺陷，或可能额外萌发成各向同性的囊泡。
Polymer vesicles are stable robust vesicles made from block copolymer amphiphiles. Recent progress in the chemical design of block copolymers opens up the exciting possibility of creating a wide variety of polymer vesicles with varying fine structure, functionality and geometry. Polymer vesicles not only constitute useful systems for drug delivery and micro/nano-reactors but also provide an invaluable arena for exploring the ordering of matter on curved surfaces embedded in three dimensions. By choosing suitable liquid-crystalline polymers for one of the copolymer components, one can create vesicles with smectic stripes. Smectic order on shapes of spherical topology inevitably possesses topological defects ( disclinations) that are themselves distinguished regions for potential chemical functionalization and nucleators of vesicle budding. Here we report on glassy striped polymer vesicles formed from amphiphilic block copolymers in which the hydrophobic block is a smectic liquid crystal polymer containing cholesteryl-based mesogens. The vesicles exhibit two-dimensional smectic order and are ellipsoidal in shape with defects, or possible additional budding into isotropic vesicles, at the poles.