Frequent malaria illness episodes in two Malawian patients on antiretroviral therapy soon after stopping cotrimoxazole preventive therapy.
Frequent malaria illness episodes in two Malawian patients on antiretroviral therapy soon after stopping cotrimoxazole preventive therapy.
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DOI：
10.4314/mmj.v29i1.12
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发表时间：
2017-03
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通讯作者：
Wongani Nyangulu;E. Mwinjiwa;T. Divala;R. Mungwira;O. Nyirenda;M. Kanjala;Gillian Mbambo;J. Mallewa;T. Taylor;M. Laurens;M. Laufer;J. V. van Oosterhout
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文献类型：
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作者：
Wongani Nyangulu;E. Mwinjiwa;T. Divala;R. Mungwira;O. Nyirenda;M. Kanjala;Gillian Mbambo;J. Mallewa;T. Taylor;M. Laurens;M. Laufer;J. V. van Oosterhout
We describe two Malawian adults on successful antiretroviral therapy who experienced frequent malaria episodes after stopping cotrimoxazole prophylaxis. We argue that, in addition to stopping cotrimoxazole, diminished malaria immunity and drug interactions between efavirenz and artemether-lumefantrine may have played a causative role in the recurrent malaria our patients experienced.
