Rodent models of prefrontal cortical function
Rodent models of prefrontal cortical function
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DOI：
10.1016/s0166-2236(02)02164-1
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发表时间：
2002-07-01
影响因子：
15.9
通讯作者：
Bowman, EM
中科院分区：
文献类型：
--
作者：
Brown, VJ;Bowman, EM
在本文中，我们探讨了对大鼠的研究是否能为有关灵长类前额叶皮层功能的争论提供有用信息。从表面上看，对不同物种前额叶皮层内区域特化的比较表明存在功能上的对应。不幸的是，灵长类前额叶皮层功能特化的本质存在争议，而且支持大鼠和灵长类前额叶皮层特定区域之间同源性这一观点的数据很薄弱。然而，我们在此认为，对大鼠相对未分化的前额叶皮层内计算功能的研究能够为理解灵长类前额叶皮层的信息处理提供启示。
In this article, we consider whether studies in rats can provide useful information regarding the debate about the functions of the primate prefrontal cortex. At a superficial level, comparison of regional specializations within the prefrontal cortices of different species suggests functional correspondence. Unfortunately, the nature of functional specialization in primate prefrontal cortex is controversial, and data supporting the idea of homology between specific areas of rat and primate prefrontal cortex are weak. Nevertheless, we argue here that studies of the computational functions within the relatively undifferentiated prefrontal cortex of rats can shed light on processing in primate prefrontal cortex.