Dietary patterns and cardiovascular disease mortality in Japan: a prospective cohort study
Dietary patterns and cardiovascular disease mortality in Japan: a prospective cohort study
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DOI：
10.1093/ije/dym005
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发表时间：
2007-06-01
影响因子：
7.7
通讯作者：
Tsuji, Ichiro
中科院分区：
文献类型：
--
作者：
Shimazu, Taichi;Kuriyama, Shinichi;Tsuji, Ichiro
背景 虽然生态观察表明日本饮食可能降低心血管疾病 (CVD) 风险，但日本饮食模式对 CVD 死亡率的影响尚不清楚。方法我们前瞻性评估了日本人饮食模式与 CVD 死亡率之间的关联。饮食信息收集自 40 547 名 40-79 岁日本男性和女性，基线时无糖尿病、中风、心肌梗塞或癌症病史，1994 年。结果 在 7 年的随访期间，801 名参与者死于 CVD。基于经过验证的食物频率调查问卷的因素分析（主要成分）确定了三种饮食模式：（i）日本饮食模式与大豆制品、鱼类、海藻、蔬菜、水果和绿茶高度相关，（ii）“动物性食品”饮食模式和（iii）高乳制品、高水果和蔬菜、低酒精（DFA）饮食模式。日本的饮食模式与高钠摄入量和高血压患病率高有关。调整潜在混杂因素后，日本饮食模式评分与较低的 CVD 死亡风险相关（最高四分位数与最低四分位数的风险比为 0.73；95% 置信区间：0.59-0.90；趋势 P=0.003）。 “动物性食品”饮食模式与 CVD 风险增加相关，但 DFA 饮食模式则不然。 结论 日本饮食模式与 CVD 死亡率风险降低相关，尽管其与钠摄入量和高血压有关。
Background Although ecological observations suggest that the Japanese diet may reduce the risk of cardiovascular disease (CVD), the impact of a Japanese dietary pattern upon mortality due to CVD is unclear.Methods We prospectively assessed the association between dietary patterns among the Japanese and CVD mortality. Dietary information was collected from 40 547 Japanese men and women aged 40-79 years without a history of diabetes, stroke, myocardial infarction or cancer at the baseline in 1994.Results During 7 years of follow-up, 801 participants died of CVD. Factor analysis (principal component) based on a validated food frequency questionnaire identified three dietary patterns: (i) a Japanese dietary pattern highly correlated with soybean products, fish, seaweeds, vegetables, fruits and green tea, (ii) an 'animal food' dietary pattern and (iii) a high-dairy, high-fruit-and-vegetable, low-alcohol (DFA) dietary pattern. The Japanese dietary pattern was related to high sodium intake and high prevalence of hypertension. After adjustment for potential confounders, the Japanese dietary pattern score was associated with a lower risk of CVD mortality (hazard ratio of the highest quartile vs the lowest, 0.73; 95% confidence interval: 0.59-0.90; P for trend= 0.003). The 'animal food' dietary pattern was associated with an increased risk of CVD, but the DFA dietary pattern was not.Conclusion The Japanese dietary pattern was associated with a decreased risk of CVD mortality, despite its relation to sodium intake and hypertension.