Synthesis, Characterization, and Binding Property of Isoelectronic Analogues of Nucleobases, B(6)-Substituted 5-Aza-6-borauracils and -thymines
Synthesis, Characterization, and Binding Property of Isoelectronic Analogues of Nucleobases, B(6)-Substituted 5-Aza-6-borauracils and -thymines
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DOI：
10.1021/ol1012058
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发表时间：
2010-08-06
期刊：
影响因子：
5.2
通讯作者：
Saigo, Kazuhiko
中科院分区：
文献类型：
--
作者：
Ito, Hiroshi;Yumura, Kyohei;Saigo, Kazuhiko
As isoelectronic BN-containing analogues of 6-substituted uracil and thymine, a series of B(6)-substituted 5-aza-6-borauracils (U(BN)s) and -thymines (T(BN)s) were synthesized and fully characterized. The crystallographic and spectroscopic analyses of the analogues revealed that the framework and hydrogen-bonding pattern of T(BN)s were similar to those of the original nucleobase, thymine.
