Primary structure of the mouse beta 1-adrenergic receptor gene.
Primary structure of the mouse beta 1-adrenergic receptor gene.
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小鼠 β1-肾上腺素能受体基因的一级结构。
DOI：
10.1016/0167-4889(93)90209-8
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发表时间：
1993
期刊：
影响因子：
--
通讯作者：
Bernstein,D
中科院分区：
文献类型：
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作者：
Jasper,JR;Link,RE;Chruscinski,AJ;Kobilka,BK;Bernstein,D
从基因组文库中分离小鼠β 1-肾上腺素能受体，并克隆到pBluescript SK−中。克隆的表征揭示了一个开放的阅读框架，其编码466个氨基酸的预测蛋白。小鼠β 1受体与人序列的同一性为92.7%，与大鼠序列的同一性为98.5%，并且在Asn-15处含有N-连接糖基化的共有位点，在Ser-301处含有cAMP依赖性蛋白激酶磷酸化位点。
The mouse β 1-adrenergic receptor was isolated from a genomic library and cloned into pBluescript SK−. Characterization of the clone revealed an open reading frame which encodes a predicted protein of 466 amino acids. The mouse β 1 receptor is 92.7% identical to the human sequence, 98.5% identical to the rat sequence, and contains a consensus site for N-linked glycosylation at Asn-15 and a cAMP-dependent protein kinase phosphorylation site at Ser-301.