The threshold for diagnosing impaired fasting glucose: a position statement by the European Diabetes Epidemiology Group
The threshold for diagnosing impaired fasting glucose: a position statement by the European Diabetes Epidemiology Group
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DOI：
10.1007/s00125-006-0189-4
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发表时间：
2006-05-01
期刊：
影响因子：
8.2
通讯作者：
Wareham, NJ
中科院分区：
文献类型：
--
作者：
Forouhi, NG;Balkau, B;Wareham, NJ
IFG这一类别是在20世纪90年代末引入的，用于表示空腹血糖（FPG）浓度在6.1至6.9 mmol/l之间的非糖尿病性高血糖状态。2003年，美国糖尿病协会建议将诊断阈值降低到5.6 mmol/l。降低门槛的理由受到了质疑。临界值的这一简单变化造成了IFG的大流行，使IFG在世界各地的流行率增加了2至5倍。这种阈值的变化具有深远的公共卫生影响。欧洲糖尿病流行病学小组（EDEG）审查了IFG定义的较低临界值的证据，并得出结论，以前的定义不应改变。EDEG进一步建议应重新考虑所有非糖尿病性高血糖分类定义的价值。
The category of IFG was introduced in the late 1990s to denote a state of non-diabetic hyperglycaemia defined by a fasting plasma glucose (FPG) concentration between 6.1 and 6.9 mmol/l. In 2003 the American Diabetes Association recommended that this diagnostic threshold be lowered to 5.6 mmol/l. The justification for lowering the threshold has been questioned. This simple change in cut-off value creates a pandemic of IFG, with a two- to five-fold increase in the prevalence of IFG across the world. Such a change in threshold has far-reaching public health implications. The European Diabetes Epidemiology Group (EDEG) has reviewed the evidence for this lower cut-off point for the definition of IFG and concludes that the previous definition should not be altered. EDEG further recommends that the value of all categorical definitions of non-diabetic hyperglycaemia should be reconsidered.