Recent advances in metal-mediated carbon-nitrogen bond formation reactions: Aziridination and amidation
Recent advances in metal-mediated carbon-nitrogen bond formation reactions: Aziridination and amidation
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DOI：
10.2174/1385272053765024
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发表时间：
2005-05-01
影响因子：
2.6
通讯作者：
Halfen, JA
中科院分区：
文献类型：
--
作者：
Halfen, JA
这篇综述描述了具有合成价值的氮丙啶和磺酰胺的均质、金属介导的催化途径的开发的最新进展。本综述中描述的研究领域包括：(a)催化铜、铁和银介导的氮宾从亚氨基碘烷转移到烯烃，(b)开发用于烯烃氮丙啶化的替代氮宾源，包括N-卤代-对甲苯磺酰胺、具有不稳定N保护基团的亚氨基碘烷和磺酰叠氮化物，(c)使用单锅氮丙啶化方案进行原位氮丙啶化产生亚氨基碘烷，以及(d)金属介导的卡宾转移至亚胺。
This review describes recent progress in the development of homogeneous, metal-mediated, catalytic pathways to synthetically valuable aziridines and sulfonamides. Areas of investigation described within this review include: (a) catalytic copper, iron, and silver-mediated nitrene transfer from the iminoiodinanes to olefins, (b) development of alternative nitrene sources for olefin aziridination, including N-halo-p-toluene sulfonamides, iminoiodinanes featuring labile N-protecting groups, and sulfonylazides, (c) use of single-pot aziridination protocols for the in situ generation of iminoiodinanes, and (d) metal-mediated carbene transfer to imines.