PROTEIN ABSORPTION BY INTESTINE OF FETAL RAT IN UTERO

PROTEIN ABSORPTION BY INTESTINE OF FETAL RAT IN UTERO
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DOI:
10.1126/science.177.4048.522
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发表时间:
1972-01-01
期刊:
影响因子:
56.9
通讯作者:
ORLIC, D
ORLIC, D
中科院分区:
综合性期刊1区
文献类型:
--
作者:
LEV, R;ORLIC, D

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辣根过氧化物酶(分子量约40,000)注射到妊娠大鼠的羊膜囊中,6至18小时后,在胎肠内的吸收细胞和下面的血管内皮细胞中进行了超微结构鉴定。这表明胎儿吞咽的羊水中的大分子蛋白质可以被胎儿肠道吸收和转运,并且可能表明生理化合物可以通过这种肠道途径转运以促进胎儿发育。
Horseradish peroxidase (molecular weight, about 40,000) injected into the amniotic sacs in pregnant rats has been identified ultrastructurally, 6 to 18 hours later, within the fetal intestine in the absorptive cells and the underlying vascular endothelium. This indicates that macromolecular protein within amniotic fluid swallowed by the fetus can be absorbed and transported by fetal intestine, and may indicate that physiological compounds can be transported by this enteric route to contribute to fetal development.