Pseudoimmune precipitation by the isolated byssinosis "antigen".
Pseudoimmune precipitation by the isolated byssinosis "antigen".
复制标题
由分离的棉尘螨“抗原”产生的假免疫沉淀。
作者：
J. Edwards;B. Jones
The so-called cotton antigen, a polymer of 5,7,3′,4′ tetrahydroxyflavan 3–4 diol (THF) extracted from cotton plant bracts, precipitated 58% IgG, 54% IgM and 15% IgA in a sample of human serum and concurrently antibody activity in this serum to three physicochemically distinct antigens was reduced by 50%, 52% and 62%, respectively. THF also reacted with five myeloma IgG at dilutions equal to, or higher than, comparable dilutions of human serum and gave positive gel diffusion reactions with H and L chains, Fab and Fc pieces of IgG.
On the basis of these results it is suggested that human immunoglobulins are nonspecifically precipitated by the tannin-like polymer.
