Integrated active tracking detector for MRI-guided interventions
Integrated active tracking detector for MRI-guided interventions
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DOI：
10.1002/mrm.23112
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发表时间：
2012-01-01
影响因子：
3.3
通讯作者：
Boero, Giovanni
中科院分区：
文献类型：
--
作者：
Anders, Jens;SanGiorgio, Paul;Boero, Giovanni
我们提出了一种完全集成的探测器，适用于MR引导介入中介入器械的主动跟踪。该单片机系统由检波线圈、调谐电容、中频下变频接收机和基于锁相环的频率合成器组成。得益于集成混频器，芯片输出级可提供0至200 kHz频率范围内的模拟下变频NMR信号。以标准互补金属氧化物半导体技术实现的微芯片具有1 × 2 × 0.74 mm 3的尺寸，并且以63 MHz的频率（即，在1.5T临床扫描仪中）。在标准临床扫描仪中的测试证明了互补金属氧化物半导体微芯片与临床MRI系统的兼容性。使用尺寸为1 x 1.9 x 0.8 mm 3的顺式聚异戊二烯固体样品作为内部信号源，检测器在100 ms的测量时间内实现了0.15 mm的三维各向同性空间分辨率。Magn Reson Med，2011年。(C)2011 Wiley-Liss，Inc.
We present a fully integrated detector suitable for active tracking of interventional devices in MR-guided interventions. The single-chip microsystem consists of a detection coil, a tuning capacitor, an intermediate frequency downconversion receiver, and a phase-locked-loop-based frequency synthesizer. Thanks to the integrated mixer, the chip output stage delivers an analog frequency-downconverted NMR signal in the frequency range from 0 to 200 kHz. The microchip, realized in a standard complementary metal oxide semiconductor technology, has a size of 1 x 2 x 0.74 mm3 and operates at a frequency of 63 MHz (i.e., in 1.5 T clinical scanners). Tests in a standard clinical scanner demonstrate the compatibility of the complementary metal oxide semiconductor microchip with clinical MRI systems. Using a solid sample of cis-polyisoprene having a size of 1 x 1.9 x 0.8 mm3 as internal signal source, the detector achieves a three-dimensional isotropic spatial resolution of 0.15 mm in a measuring time of 100 ms. Magn Reson Med, 2011. (C) 2011 Wiley-Liss, Inc.