The Premenstrual Syndrome: Effects of “Medical Ovariectomy”
The Premenstrual Syndrome: Effects of “Medical Ovariectomy”
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经前期综合症：“医学卵巢切除术”的影响
DOI：
10.1097/00006254-198509000-00015
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发表时间：
1985
影响因子：
6.2
通讯作者：
S. Yen
中科院分区：
文献类型：
--
作者：
K. Muse;N. Cetel;L. A. Futterman;S. Yen
在一项为期6个月的交叉研究中，8例经前综合征患者每日服用促性腺激素释放激素激动剂后，身体和行为症状得到缓解。用这种激动剂实现的可逆性“药物卵巢切除术”表明，它可能是这种痛苦综合征的短期有效和合理的治疗方法。长期治疗是否安全有效，甚至是必要的，仍有待确定。
In a crossover study conducted over a six-month period in eight patients with well-characterized premenstrual syndrome, physical and behavioral symptoms were relieved by daily administration of an agonist of gonadotropin-releasing hormone. The reversible "medical ovariectomy" attained with this agonist suggests that it may be an effective and rational treatment for this distressing syndrome in the short term. Whether prolonged therapy would be safe and effective, or even necessary, remains to be determined.