CHEMICAL CHARACTERIZATION OF LUNG SURFACTANT APOPROTEINS - AMINO-ACID-COMPOSITION, N-TERMINAL SEQUENCE AND ENZYMATIC DIGESTION
CHEMICAL CHARACTERIZATION OF LUNG SURFACTANT APOPROTEINS - AMINO-ACID-COMPOSITION, N-TERMINAL SEQUENCE AND ENZYMATIC DIGESTION
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DOI：
10.1042/bst0131092
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发表时间：
1985-12-01
影响因子：
3.9
通讯作者：
BENSON, BJ
中科院分区：
文献类型：
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作者：
HAWGOOD, S;EFRATI, H;BENSON, BJ
肺表面活性物质由肺泡I1型细胞分泌，通过调节周围空气空间中大空气-水界面产生的表面张力来帮助稳定肺（见Goerke， 1974）。双棕榈酰磷脂酰胆碱是肺表面活性剂的主要成分，可形成稳定的低表面膜
Pulmonary surfactant is secreted by the alveolar type I1 cell and helps to stabilize the lung by modulating the surface tension generated at the large air-water interface in the peripheral air spaces (reviewed in Goerke, 1974). Dipalmitoylphosphatidylcholine, the major component of lung surfactant, can form a stable surface film of low surface